Secretary of State
James Buchanan (1845-1849)
Secretary of the Treasury
Robert J. Walker (1845-1849)
Secretary of War
William L. Marcy (1845-1849)

Attorney General
John Y. Mason (1845-46)
Nathan Clifford (1846-48)
Isaac Toucey (1848-49)
Postmaster General
Cave Johnson (1845-1849)

Secretary of the Navy
George Bancroft (1845-46)
John Y. Mason (1846-49)